In very good condition: cover has light wear; inside is clean; page edges have some foxing. Library of Congress #68-57411
Oral Antidiabetic Therapy: A Compendium of Significant Articles on Phenformin Hydrochloride is a collection of research articles focused on phenformin hydrochloride, an oral medication used to manage diabetes mellitus. This compendium provides insights into the drug's pharmacological properties, historical context, and its role in diabetes treatment.
Pharmacological Properties
Mechanism of Action: Phenformin is part of the biguanide class of drugs, which help lower blood sugar levels.
Absorption and Metabolism: The drug is well absorbed after oral administration, with significant metabolic reactions leading to its active forms.
Historical Context
Market History: Phenformin was widely used until the late 1970s when it was withdrawn from many markets due to safety concerns, particularly the risk of lactic acidosis.
Efficacy and Safety: The compendium discusses various studies that evaluate the effectiveness and safety profile of phenformin in managing diabetes.
Research Findings
Clinical Studies: The articles include significant findings from clinical studies that assess the drug's impact on glycemic control and its side effects.
Comparative Analysis: Phenformin is compared with other antidiabetic medications, highlighting its unique properties and potential benefits.
This compendium serves as a valuable resource for understanding the role of phenformin in diabetes management, its historical significance, and ongoing research in the field of endocrinology.
